镁合金支架的生物降解
Application ID: 131521
Biodegradable metallic biomaterials such as Magnesium (Mg) are gathering attention for biomedical applications due to their favorable properties.
The present model simulates dissolution of a Mg stent in a blood vessel. Due to the circumferential symmetry, only one-twelfth of the actual geometry is used in the model.
The Level Set interface is used in a first study to model the geometrical changes of the stent when subject to a local constant dissolution rate over time.
The resulting stent shapes at various stages of dissolution are then used in a second study in order to calculate the concentration of Mg ions in the tissue and vessel surrounding the stent, and the corresponding pH levels.
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